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AN INTEGRATED MICROFLUIDIC NOZZLE DEVICE FOR CHROMATOGRAPHIC SAMPLE PREPARATION FOR MASS SPECTROMETRY APPLICATIONS
AN INTEGRATED MICROFLUIDIC NOZZLE DEVICE FOR CHROMATOGRAPHIC SAMPLE PREPARATION FOR MASS SPECTROMETRY APPLICATIONS
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机译:用于质谱法的色谱样品制备的集成微流控喷嘴装置
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摘要
In accordance with one aspect of the present invention, a low-cost injection-molded plastic microfluidic device that performs the multiplexing of affinity or chromatographic sample cleanup and enrichment methods and the detection by nanospray mass spectrometry of analytes such as biomarkers in a single package to conserve sample, and processes body fluids with HPLC grade and even next- generation chromatographic resins such as nanoparticles to maximize the sensitivity of the detection.
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