MINIATURIZED 62ZN/62CU GENERATOR FOR HIGH CONCENTRATION CLINICAL DELIVERY OF 62CU KIT FORMULATION FOR THE FACILE PREPARATION OF RADIOLABELED CU-BIS(THIOSEMICARBAZONE) COMPOUNDS

摘要

A new system accomplishes easy, interchangeable production of multiple PET radiopharmaceuticals through the use of a simplified eluant-only generator and a kit based synthesis technique employing lyophilized or freeze dried ligand. Thus, by simply switching the lyophilized ligand vial kit, any number of 62Cu-labeled radiopharmaceuticals (62Cu-ligand) can be interchangeably synthesized with only one 62Zn/62Cu generator.