1H-PYRAZOLO3,4-DPYRIMIDINE, PURINE, 7H-PURIN-8(9H)-ONE, 3H-1,2,3TRIAZOLO4,5-DPYRIMIDINE, AND THIENO3,2-DPYRIMIDINE COMPOUNDS, THEIR USE AS mTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES

摘要

The invention relates to 1H-pyrazolo[3,4-d]pyrimidine, purine, 7H-purin-8(9H)-one, 3H-[1,2,3]triazolo[4,5-d]pyrimidine, and thieno[3,2-d]pyrimidine compounds, compositions comprising the compounds, and methods for making and using the compounds.