5-FLUORO-3α,17β-DIHYDROXY-5α-ANDROSTAN-6-ONE, THE METHOD FOR ITS PRODUCTION AND ITS USE FOR INFLUENCING OF PLANT GROWTH

摘要

5-Fluoro-3α,17β-dihydroxy-5α-androstan-6-one IV and the method of its production are described. The synthesis consists of partial hydrolyses of 5-fluoro-6-oxo-5α-androstan-3β,17β-diyl diacetate with mild alkaline agent to 5-fluoro-3β-hydroxy-6-oxo-5α-androstan-17β-yl acetate that on solvolytic change of hydroxyl configuration in position 3 affords 5-fluoro-3α-hydroxy-6-oxo-5α-androstan-17β-yl acetate, which on deprotection afforded desired 5-fluoro-3α,17β-dihydroxy-5α-androstan-6-one IV. The invention relates also to the use of 5-fluoro-3α,17β-dihydroxy-5α-androstaii-6-one IV for influencing of plant growth, especially for increasing of plant yield and also for removal of plant stresses.