首页> 外国专利> ORAL PHARMACEUTICAL FORMULATION COMPRISING A SOLUBLE OR DISPERSIBLE SINGLE-UNIT DOSE TABLET, SUCH AS AN EFFERVESCENT TABLET

ORAL PHARMACEUTICAL FORMULATION COMPRISING A SOLUBLE OR DISPERSIBLE SINGLE-UNIT DOSE TABLET, SUCH AS AN EFFERVESCENT TABLET

机译:包含可溶或可分散的单单位剂量片剂的口服药物制剂,例如泡腾片

摘要

The invention relates to a formulation comprising a mixture containing at least one active principle and a combination of excipients including: a binder, a hydrophobic non-soluble compression lubricant and a surfactant which, together with the lubricant, has an affinity for increasing the wettability thereof and assuring dispersion during the disintegration of the tablet in the liquid. For example, the lubricant is magnesium steriate and the surfactant is a foaming agent such as sodium laurylsulfate.
机译:本发明涉及一种制剂,其包含含有至少一种活性成分的混合物和赋形剂的组合,所述赋形剂包括:粘合剂,疏水性不溶性压缩润滑剂和表面活性剂,所述表面活性剂与所述润滑剂一起具有增加其润湿性的亲和力。并确保片剂在液体中崩解时的分散。例如,润滑剂是硬脂酸镁,表面活性剂是发泡剂,例如月桂基硫酸钠。

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