Method for the elution of 18F fluoride trapped on an anion-exchange resin in a form suitable for efficient radiolabeling without any evaporation step

摘要

The present invention relates to a method to extract out of an aqueous solution, concentrate and/or reformulate [18F] fluorides without any evaporation step, characterised in that the eluting solution is a low water content, preferably 3% water, organic solution containing at least:- a first compound (A) which is a tertiary alcohol-function bearing molecule,- a second compound (B) which is a phase transfer agent suitable for radiolabeling and which is necessary to the anion exchange process.