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The combination of a serotonin reuptake inhibitor and a 5-HT2C antagonist, inverse agonist or partial agonist

机译:血清素再摄取抑制剂和5-HT2C拮抗剂,反向激动剂或部分激动剂的组合

摘要

The present invention relates to the use of compounds and compositions of compounds having serotonin reuptake inhibiting activity and 5-HT2C antagonistic, partial agonistic or inverse agonistic activity for the for the treatment of depression and other affective disorders. The combined serotonin reuptake inhibiting effect and the 5-HT2C antagonistic, partial agonistic or inverse agonistic effect may reside within the same chemical compound or in two different chemical compounds.
机译:本发明涉及具有5-羟色胺再摄取抑制活性和5-HT 2C 拮抗,部分激动或反激动活性的化合物和化合物组合物在治疗抑郁症和其他情感障碍中的用途。 5-羟色胺再摄取抑制作用与5-HT 2C 拮抗,部分激动或反向激动作用共同存在于同一化合物中或两种不同化合物中。

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