首页> 外国专利> PEPTIDE SUBSTANCE STIMULATING REGENERATION OF CENTRAL NERVOUS SYSTEM NEURONS, PHARMACEUTICAL COMPOSITION ON ITS BASE, AND THE METHOD OF ITS APPLICATION

PEPTIDE SUBSTANCE STIMULATING REGENERATION OF CENTRAL NERVOUS SYSTEM NEURONS, PHARMACEUTICAL COMPOSITION ON ITS BASE, AND THE METHOD OF ITS APPLICATION

机译:中央神经系统神经元的肽物质刺激再生,基于其的药物成分及其应用方法

摘要

The invention is related to the medicinal means of treatment of diseases, traumas, as well as consequences of traumas of the central nervous system, and can be also used as a means of stimulating neurons regeneration. There is proposed a peptide glutamyl-aspartyl-arginine with general formula H-GIu-Asp-Arg-OH sequence 1 [SEQ ID NO:1] capable of stimulating the regeneration of neurons. There is also proposed a pharmaceutical composition stimulating the regeneration of neurons containing peptide glutamyl-aspartyl-arginine with general formula H-GIu-Asp-Arg-OH sequence 1 [SEQ ID NO:1] as its active base, as well as a pharmaceutically acceptable carrier. There is proposed a method of stimulating the regeneration of neurons consisting in the administration to a patient of the pharmaceutical composition, containing peptide glutamyl-aspartyl-arginine with general formula H-Glu-Asp-Arg-OH sequence 1 [SEQ ID NO:1] as its active base, in the dose of 0,01-100 mug/kg of body weight at least once a day during a period necessary for attaining the therapeutic effect, such administration being performed parenterally.
机译:本发明涉及治疗疾病,外伤以及中枢神经系统外伤的后果的药物手段,并且还可以用作刺激神经元再生的手段。提出了一种肽谷氨酰胺-天冬氨酰-精氨酸,其具有能够刺激神经元再生的通式H-Glu-Asp-Arg-OH序列1 [SEQ ID NO:1]。还提出了一种药物组合物,其可刺激含有通式H-Glu-Asp-Arg-OH序列1 [SEQ ID NO:1]的肽谷氨酰-天冬氨酰-精氨酸的神经元的再生,以及药用组合物。可接受的载体。提出了一种刺激神经元再生的方法,该方法包括向患者给药包含具有通式H-Glu-Asp-Arg-OH序列1 [SEQ ID NO:1]的肽谷氨酰-天冬氨酰-精氨酸的药物组合物。以其活性碱为基础,在达到治疗效果所必需的时间内,每天至少以0.01-100马克/千克体重的剂量服用,这种给药是非肠道的。

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