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MAKERS FOR THE DIAGNOSIS OF PROGNOSIS OF RHEUMATOID ARTHRITIS USING DNMT3B GENE AND METHOD FOR PREDICTING SEVERITY AND ANALYZING PROGNOSIS OF RHEUMATOID ARTHRITIS USING THE SAME
MAKERS FOR THE DIAGNOSIS OF PROGNOSIS OF RHEUMATOID ARTHRITIS USING DNMT3B GENE AND METHOD FOR PREDICTING SEVERITY AND ANALYZING PROGNOSIS OF RHEUMATOID ARTHRITIS USING THE SAME
A maker for diagnosing the prognosis of rheumatoid arthritis by using DNMT3B(DNA-methyltransferase-3B) gene is provided to diagnose patients with severe rheumatoid arthritis by finding a genotype with high danger of articulation breakdown for rheumatoid arthritis. A maker for diagnosing the prognosis of rheumatoid arthritis comprises polynucleotides including 10-200 successive nucleotides containing the 548th base of a DNMT3B gene of the sequence number 1 or polynucleotides complementary with the polynucleotides. The 548th base of a DNMT3B gene of the sequence number 1 is selected from the genotype consisting of CC, CT and TT.
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