PHARMACEUTICAL COMPOSITION OF ENTERIC SUSTAINED RELEASE TABLETS CONTAINING IBUDILAST AS AN ACTIVE INGREDIENT AND PREPARATION METHOD OF THEREOF

摘要

The delayed release pharmaceutical composition and its preparation method of one intestines are arranged to simplify the procedures, by saving prilling and dry method, improving production reproducibility and saving cost. The delayed release pharmaceutical composition of one intestines is as 2~50 components that an active component includes by Ibudilast weight; 1~60 component as a delayed release additive is by ethyl cellulose weight; 1~40 component is selected from the weight of group by least one comprising the hydroxypropyl methylcellulose phthalate and hydroxypropylmethylcellulose acetate succinate of the additive as an intestines.