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SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES COATED WITH MANNAN, PREPARATION METHOD THEREOF AND CONTRAST AGENT FOR DIAGNOSING LIVER DISEASES
SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES COATED WITH MANNAN, PREPARATION METHOD THEREOF AND CONTRAST AGENT FOR DIAGNOSING LIVER DISEASES
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机译:甘露聚糖包覆的超顺磁性氧化铁纳米粒子及其制备方法和造影剂
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摘要
A mannan-coated superparamagnetic iron oxide nanoparticle is provided, which enables specific flow of liver to kupffer cell and ensure stability of ferrofluid. A contrast media for diagnosing hepatism comprises a mannan coated superparamagnetic iron oxide nanoparticle. A method for manufacturing the nanoparticle comprises: a step of adding basic solution in iron chloride aqueous solution and dipping iron oxide nanoparticle; a step of oxidizing the iron oxide nanoparticle and producing storage solution; and a step of mixing mannan solution in the storage solution, stirring and coating.
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