Stereoselective preparation method of tri-O-acetyl-5-deoxy-β-D-ribofuranose and separation method thereof

摘要

The present invention discloses a method for preparing highly pure tri-O-acetyl-5-deoxy-ß-D-ribofuranose which comprises a highly stereoselective acetylation step of 1-methylacetonide, and the pure ß-anomer thus obtained can be advantageous used for preparing capecitabine.