Antibody for cardiac ankyrin repeat protein

摘要

heart hyacinth Kirin repeat protein (Cardiac ankyrin repeat protein) is a protein expressed in the embryonic heart, such as high blood pressure is expressed in cardiomyocytes of the heart or heart failure overload condition is known as increasing protein. This protein, by inhibiting the expression of the cardiac gene expression in the remodeling process, but the myocardial protection effect and speculated that the exact function was not known. The present invention was to find a way to detect this protein in the tissue as the progress in the study of the heart hyacinth Kirin repeat protein (Cardiac ankyrin repeat protein), 23 rats in the CARP base sequence of 9 amino acids, 92 subcutaneous injection in rabbits by specifying a 106 times by creating a peptide sequences were identified from time to detect the cellular level and also at the organizational level the CARP protein effectively by producing antibodies.