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METHOD FOR IMPROVING THE STRUCTURE AND / OR FUNCTIONS OF ARTERIOL, ACTIVE AGENT FOR IMPROVING THE STRUCTURE AND / OR FUNCTIONS OF ARTERIOL AND KIT FOR TREATMENT OF CONDITIONS, CHARACTERIZING NENORMURALURIC ARENOLURICULT
METHOD FOR IMPROVING THE STRUCTURE AND / OR FUNCTIONS OF ARTERIOL, ACTIVE AGENT FOR IMPROVING THE STRUCTURE AND / OR FUNCTIONS OF ARTERIOL AND KIT FOR TREATMENT OF CONDITIONS, CHARACTERIZING NENORMURALURIC ARENOLURICULT
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机译:改善动脉的结构和/或功能的方法,用于改善状况的动脉和套件的活性剂,表征神经性肾上腺皮质激素
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摘要
The present invention relates to the unexpected finding that vessels smaller than even the smallest arteries (i.e. arterioles) thicken, become dysfunctional and cause end organ damage to tissues as diverse as the brain and the kidney. This invention provides a method to improve the structure and function of arterioles and preserve the function of end organs such as the brain and kidney. In certain embodiments, the methods involve administering to a human having thickened arterioles in brain, kidney or alveoli a peptide that ranges in length up to 30 amino acids, and that comprises a class A amphipathic helix, and bears at least one protecting group.
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