THIOMORPHOLINE DERIVATIVES OF STEROIDS, THEIR USE IN MAKING MEIOSIS REGULATING MEDICINAL PREPARATIONS AND METHOD OF PRODUCING THESE COMPOUNDS

摘要

FIELD: chemistry.;SUBSTANCE: description is given of thiomorpholine derivatives of steroids with general formula I . These steroids are characterised by presence of a thiomorpholine fragment, bonded to a C¹⁷ steroid skeleton through an alkylene spacer, where R⁴ and R^4' are hydrogen and methyl, under the condition that, both R⁴ and R^4' represent hydrogen at the same time.;EFFECT: invention can be successfully used for stimulating meiosis of human oocyte.;12 cl, 2 ex, 5 tbl, 6 dwg