or 6-O-[β-D-(2,3,4,6-tetra-O- acetyl)galactopyranosyl]-d,1-α-tocopherol (2), consisting in interaction of α-tocopherol and α- or β-anomer of related D-gluco- or D-galactopyranose pentaacetates with added catalyst systems: BF3·OEt2 ionic liquid [bmim]PF6 at mole ratio α-tocopherol:sugar pentaacetate: BF3·OEt2:[bmim]PF6 = 1:1:2.5:0.3-5, in methylene chloride within 3 h at room temperature.;EFFECT: given compounds are precursors of related deacetylated glycosides with observed antiallergic and anti-inflammatory activity.;1 cl, 8 ex"/>
METHOD OF 6-O-amp;beta;-D-(2,3,4,6-TETRA-O-ACETYL)GLUCOPYRANOSYL-d,l-amp;alpha;-TOCOPHEROL PRODUCTION
FIELD: chemistry; pharmacology.;SUBSTANCE: invention refers to method of 6-O-[β-D-(2,3,4,6-tetra-O-acetyl)glucopyranosyl]-d,1-α-tocopherol (1) or 6-O-[β-D-(2,3,4,6-tetra-O- acetyl)galactopyranosyl]-d,1-α-tocopherol (2), consisting in interaction of α-tocopherol and α- or β-anomer of related D-gluco- or D-galactopyranose pentaacetates with added catalyst systems: BF3·OEt2 ionic liquid [bmim]PF6 at mole ratio α-tocopherol:sugar pentaacetate: BF3·OEt2:[bmim]PF6 = 1:1:2.5:0.3-5, in methylene chloride within 3 h at room temperature.;EFFECT: given compounds are precursors of related deacetylated glycosides with observed antiallergic and anti-inflammatory activity.;1 cl, 8 ex
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机译：领域：化学;药理学：本发明涉及6-O- [β-D-（2,3,4,6-四-O-乙酰基）吡喃葡萄糖基] -d，1-α-生育酚（1）<图片文件=“ 00000003.GIF” he =“ 37” id =“ imag00000003” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 58” />或6-O-[＆beta; -D-（2,3 ，4,6-四-O-乙酰基）吡喃半乳糖基] -d，1-α-生育酚（2）<图像文件=“ 00000004.GIF” he =“ 37” id =“ imag00000004” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 60” />，由相关D-葡萄糖-或D-吡喃半乳糖五乙酸酯的α-生育酚和α-或β-异头物与添加的催化剂体系的相互作用组成：BF 3 ＆middot; OEt 2 离子液体[bmim] PF 6 ，摩尔比为＆alpha;-生育酚：五乙酸糖：BF 3 ＆middot ; OEt 2 ：[bmim] PF 6 = 1：1：2.5：0.3-5，在室温下3小时内在二氯甲烷中;效果：给定化合物为具有观察到的抗过敏和抗炎活性的相关脱乙酰基糖苷的前体。; 1 cl，8 ex
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