Synthesis of 2,3,4,6-tetra-O-acetyl-beta-D-gluco(galacto)pyranosylcaprolactams and 2,3,4,6-tetra-O-acetyl-beta-D-gluco(galacto) pyranosylpyrrolidones

摘要

A new synthesis of certain lactam-containing N-glycosides was developed. 2,3,4,6-Tetra-O-acetyl-beta-D-gluco(galacto)pyranosylcaprolactams and 2,3,4,6-tetra-O-acetyl-beta-D-gluco(galacto)pyranosylpyrrolidones were synthesized by condensation at room temperature of acetobromoglucose and acetobromogalactose with epsilon-caprolactams and alpha-pyrrolidone.