NITROSATED AND NITROSYLATED NEBIVOLOL, METABOLITE, COMPOSITION OF THE SAME AND METHOD OF USE OF THE SAME

摘要

PPROBLEM TO BE SOLVED: To provide novel nitrosated and/or nitrosylated nebivolols or the like for treating cardiovascular diseases. PSOLUTION: The invention describes novel compositions comprising: a nitrosated and/or nitrosylated metabolite of nebivolol, at least one nitrosated and/or nitrosylated nebivolol and/or at least one nitrosated and/or nitrosylated metabolite of nebivolol, at least one nitric oxide donor and/or at least one antioxidant or a pharmaceutically acceptable salt thereof, and/or at least one nitrosated compound used to treat cardiovascular diseases; and nebivolol and/or at least one metabolite of nebivolol and at least one nitric oxide donor, and at least one antioxidant or the pharmaceutically acceptable salt thereof. PCOPYRIGHT: (C)2011,JPO&INPIT