POLYMER NANOPARTICLE AND CONTRAST AGENT FOR OPTICAL MOLECULAR IMAGING

摘要

PROBLEM TO BE SOLVED: To provide polymer nanoparticles excellent in FRET (fluorescent resonance energy transfer) efficiency and dispersibility, and a contrast agent for optical molecular imaging using the same.;SOLUTION: The polymer nanoparticles each having a fluorescent dye dispersed in the matrix of a fluorescent polymer are characterized in that the surface of the nanoparticles is protected by a surfactant, and fluorescence is emitted via FRET between the fluorescent polymer and the fluorescent dye, and also provided is a contrast agent for optical molecular imaging using the polymer nanoparticles.;COPYRIGHT: (C)2010,JPO&INPIT