Human corneal epithelial cell lines immortalized

摘要

The present invention in normal epithelial cells of the human cornea, the extent that can be effectively used to test for screening molecules potentially inflammatory, genetically and are physiologically similar, human corneal epithelial cell line I provide. and A can be stratified, and immortalized specific metabolic markers in human epithelial cells do not, immortalized non human corneal epithelial-specific marker on the specific metabolic differentiation markers and inflammatory response in cells capable of expressing the immortalized human corneal epithelial cell line, mutagenic effect of some agents to the cornea of ​​the cellular metabolism, a method for identifying toxic or beneficial effect, the cell lines The cultures containing, with respect to the metabolism of human corneal cells, characterized in that reacted with the considered agent to have the above action and then measuring the effects on the cell line of the agent, and the cell line The use of diagnostic kits and the cell line to use. .BACKGROUND 2