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Gold-plated stent coated with chemical substance, gold-plated stent bound with oligonucleotide, and method for producing the same
Gold-plated stent coated with chemical substance, gold-plated stent bound with oligonucleotide, and method for producing the same
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机译:涂覆有化学物质的镀金支架,结合有寡核苷酸的镀金支架及其制造方法
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摘要
The present invention relates to a gold-plated stent and its preparation method. More specifically, it relates to a gold-plated stent that is coated with various chemical materials such as 2-aminoalkanethiol, epihalogenhydrin, and diamine compounds in a sequence and also oligonucleotide gold-plated stent, which is prepared by binding oligonucleotide, a biomaterial, to the gold-plated stent coated with said chemicals. The oligonucleotide gold-plated stent of the present invention has an advantages of raising the local concentration in injured parts and minimizing the toxicity overall the body, so it can be used for prevention of restenosis after angioplasty.
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