8-oxa-1,4-diazaspiro 4,5 dec-3-en-1-yl and 1,4,8-triazaspiro as GlyT1 transporter inhibitors in the treatment of neurological and neuropsychiatric disorders 4,5 dec-3-en-1-ylacetamide derivatives

摘要

Compounds of formula (I) or a salt thereof are provided: wherein R1, R2, R3, R4, R5, R6, R7, R9, R10, X, n, p and m are as defined in the description. Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder are also disclosed. The invention further discloses pharmaceutical compositions and combinations comprising the compounds.