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Directly mass spectrometry of the medicine candidacy which the protein mixture tageteingu is done

机译:蛋白质混合物tageteingu完成的候选药物的直接质谱分析

摘要

As for this invention, high mass matrix support laser desorption ionization (MALDI) method, and the automation high throughput application which use mass spectrometry are included the characterization of the effect which medicine candidacy causes, to the protein mixture of the protein - protein interaction and the like in the sample or compound biological matrix which was refined and for quantitative analysis, kiyarakutarizeshiyon of optimization and the medicine of lead/read chemical compound, it regards using this method because of medicine production process, and medicine quality control process.
机译:对于本发明,高质量基质支持激光解吸电离(MALDI)方法和使用质谱法的自动化高通量应用包括表征药物候选性对蛋白质-蛋白质相互作用和蛋白质相互作用的蛋白质混合物的影响。精制后用于定量分析的样品或化合物生物基质中的类似物,最优化试剂和铅/读取化合物的药物,由于药物生产过程和药物质量控制过程而被认为是使用该方法。

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