The method of monitoring the medicine effectiveness in the diabetes patient who uses the assay concerning 1,5 un hydro D glucitol

摘要

HbA1c measurement is the element which is indispensable to diabetes management, but the important restriction of HbA1c as a measurement method of the blood glucose is lack of timeliness, (as for that, from the fact that it is measurement of average glucose level concerning the long period of time, the diabetes patient who is managed appropriately (HbA1c8) it does not detect the latent blood glucose fluctuation level in). HbA1c from 2 concerning 3 months low averages the both of the blood glucose symptom and the high blood glucose symptom, therefore in the high blood glucose symptom after the food, does not reflect improvement appropriately. Also 1,5 AG, is the marker of blood glucose management concerning the brief framework 2 weeks from 1, but HbA1c it possesses the mechanism which differs. 1,5 AG peculiarity from biological and physiology feature, that is a sensitivity in the high blood glucose episode of acuteness and temporariness, therefore, it is the index whose glucose fluctuation is better. The peptide characteristic diabetes medicine of puramurinchido and ekusenachido etc has peculiar action mechanism, the blood glucose effect of these medicines is not shown appropriately depending upon HbA1c. 1,5 AG which is effective measurement method of glucose fluctuation makes the latent curative effect of these medicines clear, it is possible at the same time to help the adjustment of those dosages.