EXTERMINATION OF PATHOGENIC MICROORGANISM IN ORAL CAVITY AND IMPROVING AGENT FOR BACTERIAL FLORA IN ORAL CAVITY

摘要

PPROBLEM TO BE SOLVED: To provide an improving agent for a bacterial flora in oral cavity, a tooth-cleaning agent, a gargle, a coating agent and a gum agent, each comprising a microorganism and a microbial metabolite. PSOLUTION: The improving agent for the bacterial flora in oral cavity, the tooth-cleaning agent, the gargle, the coating agent and the gum agent comprise Clostridium butyricum and a metabolite produced by reproductive activity of the Clostridium butyricum. The preparation for oral cavity is useful for prevention and treatment of a periodontal disease, dental caries, gingivitis, inflammation caused by a chemical or physical damage of an oral mucosa, ozostomia and the like. PCOPYRIGHT: (C)2010,JPO&INPIT