Method and apparatus for the assay of drug candidates for the pharmacokinetic parameter estimation related to the drug candidate

摘要

(57) Abstract Method and the device for the assay of medicine candidacy ones by the biosensor which possesses the being susceptible surface connection organism molecule of 1 or more where it is related with medicine candidacy ones are disclosed. The same method measures the connection interaction with medicine candidacy one and the being susceptible surface connection organism molecule, of 1 or more of the biosensor the process which obtains the estimator regarding at least one connection interaction parameter of medicine candidacy ones, next, by comparison with the numerical system which it correlates from the connection interaction data which is related estimator of this connection interaction parameter, to known medicine chemical compound, is related to medicine candidacy ones, the process which at least decides one estimator absorption, distribution, concerning metabolism or excretion (ADME) the medicine movement parameter, is included.