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Application of synovial mesenchymal stem cells (MSCs) to cartilage and meniscal regeneration
Application of synovial mesenchymal stem cells (MSCs) to cartilage and meniscal regeneration
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机译:滑膜间充质干细胞(MSCs)在软骨和半月板再生中的应用
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摘要
An object of the present invention is to provide a method for treating defects of articular cartilage or meniscus of a patient using in vivo chondrogenesis of synovium-derived MSCs. The present invention provides a method for treating a disease associated with defects of cartilage or meniscus. In the present invention, the method for treating a disease associated with defects of cartilage or meniscus comprises the following steps: culturing ex vivo autologous synovium-derived mesenchymal stem cells (MSCs); implanting the MSCs such that said cartilage defect site or meniscal defect site is covered by the MSCs; and regenerating cartilage tissue at the cartilage defect site or meniscal defect site in situ by differentiating the MSCs into cartilage cells.
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