首页> 外国专利> APPLICATION OF SYNOVIUM-DERIVED MESENCHYMAL STEM CELLS (MSCS) FOR CARTILAGE OR MENISCUS REGENERATION

APPLICATION OF SYNOVIUM-DERIVED MESENCHYMAL STEM CELLS (MSCS) FOR CARTILAGE OR MENISCUS REGENERATION

机译:滑膜间充质干细胞(MSCS)在软骨或半月板再生中的应用

摘要

PROBLEM TO BE SOLVED: To provide a method for treating defects of articular cartilage or meniscus using in vivo chondrogenesis of synovium-derived MSCs.SOLUTION: The present invention provides a method for treating a disease associated with defects of cartilage or meniscus. In the present invention, the method for treating a disease associated with defects of cartilage or meniscus comprises the following steps: culturing ex vivo autologous synovium-derived MSCs; implanting the MSCs such that the cartilage defect site or meniscal defect site is covered by the MSCs; and regenerating cartilage tissue at the cartilage defect site or meniscal defect site in situ by differentiating the MSCs into cartilage cells.
机译:要解决的问题:提供一种使用滑膜来源的MSC的体内软骨生成来治疗关节软骨或半月板缺陷的方法。解决方案:本发明提供一种用于治疗与软骨或半月板缺陷相关的疾病的方法。在本发明中,治疗与软骨或半月板缺陷有关的疾病的方法包括以下步骤:培养离体自体滑膜来源的MSC;植入MSC,使软骨缺损部位或半月板缺损部位被MSC覆盖;通过将MSCs分化为软骨细胞,原位在软骨缺损部位或半月板缺损部位再生软骨组织。

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