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Fluorescent silica particle composition for the target biomolecule labeling or target cell labeling, and flow cytometry multiplex sequencing kit for cytometry using this

机译:用于目标生物分子标记或目标细胞标记的荧光硅石颗粒组合物,以及使用该试剂盒的流式细胞仪多重测序试剂盒

摘要

PROBLEM TO BE SOLVED: To provide a quantitative determination system for a biomolecule, a quantitative determination method therefor, a system for detecting and sampling cells, a detection-preparative fractionation method therefor, using a fluorescent silica particle capable of varying a characteristic, as a capturing or labeling bead, in a flow cytometry, the fluorescent silica particle used therefor, and a kit combined with the plurality of silica particles.;SOLUTION: The fluorescent silica particle for labeling the target biomolecule has a fluorochrome compound bonded or adsorbed chemically with a silica component, has 300 nm or more of average particle size, and is used as a discoloration-resistant labeling bead in the flow cytometry. The fluorescent silica particle for labeling the target cell has a fluorochrome compound bonded or adsorbed chemically with a silica component, has 10-100 nm of average particle size, and is used as a discoloration-resistant labeling bead in the flow cytometry.;COPYRIGHT: (C)2009,JPO&INPIT
机译:解决的问题:为了提供用于生物分子的定量测定系统,其定量测定方法,用于检测和采样细胞的系统,用于其检测-制备的分级分离方法,使用能够改变特性的荧光二氧化硅颗粒作为样品。在流式细胞仪中捕获或标记珠子,用于其的荧光硅石颗粒以及与多个硅石颗粒组合的试剂盒;解决方案:用于标记目标生物分子的荧光硅石颗粒具有与化合物化学键合或吸附的荧光染料二氧化硅组分,平均粒径为300 nm或更大,在流式细胞仪中用作抗变色标记珠。用于标记靶细胞的荧光二氧化硅颗粒具有与二氧化硅组分化学键合或吸附的荧光染料,平均粒径为10-100 nm,在流式细胞仪中用作抗变色标记珠。 (C)2009,日本特许厅&INPIT

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