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Method for enhancing immune response using electroporation-assisted vaccine administration and booster administration
Method for enhancing immune response using electroporation-assisted vaccine administration and booster administration
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机译:使用电穿孔辅助疫苗施用和加强疫苗施用增强免疫应答的方法
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摘要
Disclosed are methods of enhancing immune responses. Such methods involve the administration of vaccine compositions to different tissues to elicit an enhanced immune response. The enhanced response arises from the vaccination and boosting route of administration in two separate patient tissues, for example, by first administering a priming vaccination into skin and later administering a boost vaccination in muscle. In each case, priming and boosting, the administration of the vaccine composition is preferably carried out using contemporaneous electroporation-assisted delivery of the antigenic agent.
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