A combination of a substance that causes necrosis and a substance that is activated by necrosis, used to selectively treat tumors and inflammatory diseases

摘要

The invention relates to a combination of substances (component I) inducing necrosis in tumors or inflamed tissue with other nontoxic substances ("prodrugs", component II). The enzymes set free by necrotic processes then cleave the nontoxic "prodrug" into the toxic "drug", which leads to massive tumor cell death and/or remission of inflammation.