Use of YB-1 in vitro for the control of the adenovirus E2 late promoter and use of nucleic acid constructs exploiting this use for the manufacture of a medicament for the treatment of tumors

摘要

The invention relates to a nucleic acid construct comprising an adenoviral E2 late promoter or a fragment thereof and a nucleic acid. The nucleic acid is selected from the group of transgenes, genes and nucleic acids which are respectively different from adenoviral nucleic acid controlled by an E2 late promoter. The invention also relates to the uses of said nucleic acid construct.