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It possesses bigger external surface product than bigger median

机译:它具有比中位数更大的外表面积

摘要

This invention regards the granular composition which in order to deliver the medicine to lung system is improved. The method of identifying the optimum form of the aerodynamics light particle where the applicants can disperse high-level is disclosed. The particle of this invention collapses at the time of processing the particle formation, is produced the hollow spherical medicine particle which is the wrinkle of very low envelope density, brings the medicine particle of the thin wall (namely, the ancestral particle) by producing. Furthermore, when as for the applicants, surface area parameter () is larger than 2, optimumly is larger than 3, this particle discovered the fact that especially it is optimum to the inhalation aerosol.
机译:本发明涉及颗粒状组合物,其为了将药物递送至肺系统而得到了改进。公开了确定空气动力学轻粒子的最佳形式的方法,其中申请人可以在其中分散高水平。本发明的颗粒在加工颗粒形成时崩解,生产出包膜密度非常低的皱纹的中空球形药物颗粒,通过生产带来了薄壁的药物颗粒(即祖先颗粒)。此外,在申请人的表面积参数()大于2,最优选大于3的情况下,该粒子发现特别是对于吸入气溶胶而言最佳的事实。

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