And compatible with the improvement of the cooling effect of the liquid target the improvement of the pressure resistance of the target, suppress enough boiling of the liquid target. Radioisotope production device, and a target 20 having a cyclotron for irradiating radiation, a receiving recess 40 for accommodating the target liquid L. Receiving recess 40 includes a bottom surface 48 of the spherical recessed in a direction away from the opening 44 and the opening 44 for introducing the radiation emitted from a cyclotron, so as to have a top 58. The intersection of the bottom surface 48 and the irradiation axis X of the radiation emitted from the cyclotron, the target 20 is arranged so as to be directly below the top 58.
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