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Kit and inspection method of MALT lymphoma

机译:MALT淋巴瘤的试剂盒和检查方法

摘要

The present invention aims to provide a kit for carrying out the method and a test method of MALT lymphomas that provide gene diagnostic data available identification of disease type and diagnosis of MALT lymphoma, development of pathology, to predict the onset and. Cancer-associated genes or tumor suppressor genes of two or more in a sample, in particular, to select two or more genes from a gene cluster consisting of 11 genes and to determine the state of the regulation of gene expression or the expression level of genes selected. Early high sensitivity and high precision on the basis that it is quantifying gene products in particular, it is checked by the detection of methylation frequency modulation of expression, or to create the expression profile of the genes on the basis of the quantitative results I do detection and diagnosis. It is possible to obtain data for evaluating the likelihood of progression to disease type in need of treatment also for MALT lymphoma diagnosis, data for early detection of progression to poor prognosis disease type addition.
机译:本发明的目的是提供一种用于进行MALT淋巴瘤的方法和测试方法的试剂盒,该试剂盒提供了可用于疾病类型的鉴定和MALT淋巴瘤的诊断,病理学发展,预测发病和预测的基因诊断数据。样本中两个或多个以上的癌症相关基因或抑癌基因,特别是从11个基因组成的基因簇中选择两个或多个基因,并确定基因表达调控的状态或基因的表达水平已选择。早期的高灵敏度和高精度(特别是在定量基因产物的基础上),可以通过检测表达的甲基化频率来进行检查,或者根据我做的定量结果来创建基因的表达谱和诊断。可能获得用于评估也需要进行治疗以用于MALT淋巴瘤诊断的疾病类型的可能性的数据,以及用于早期检测发展为不良预后疾病类型的进展的数据。

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