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USE OF HMG-COA REDUCTASE AND FARNESYL-PYROPHOSPHATE SYNTHASE INHIBITORS FOR THE PREPARATION OF A MEDICINE
USE OF HMG-COA REDUCTASE AND FARNESYL-PYROPHOSPHATE SYNTHASE INHIBITORS FOR THE PREPARATION OF A MEDICINE
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机译:HMG-COA还原酶和法尼基焦磷酸合酶抑制剂在制备药物中的用途
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摘要
The invention relates to the use of a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor and of a farnesyl-pyrophosphate synthase inhibitor, or of one of their associated physiologically acceptable salts, in the preparation of a composition, particularly a pharmaceutical composition, for use in the treatment of human or animal, pathological or nonpathological situations related to the accumulation and/or the persistence of prenylated proteins in cells, such as during progeria (Hutchinson-Gilford syndrome), restrictive dermopathy or physiological aging.
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