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OPTICALLY ACTIVE ORGANIC ACIDATE-BRIDGED DINUCLEAR PLATINUM(II) COMPLEX

机译:光学活性有机酸桥接的铂(II)络合物

摘要

The present invention is an optically active organic acidate-bridged dinuclear platinum(II) complex represented by the general formula (I):; ;or the general formula (I′):; (wherein R1 and R2 are the same or different and each represent a hydrogen atom or an alkyl group, or form an alkylene group by binding to each other at the ends thereof; R3 and R4 are the same or different and each represent a hydrogen atom or an alkyl group, or form an alkylene group by binding to each other at the ends thereof; A represents a single bond or a methylene group; and Xrepresents an anion). ;The complex of the present invention has an excellent anticancer activity, and is useful as medicine, especially an anticancer agent.
机译:本发明是由通式(I)表示的旋光性有机酸盐桥连的双核铂(II)配合物: ;或通式(I'): (其中R 1 和R 2 相同或不同,分别代表氢原子或烷基或通过在其末端彼此结合形成亚烷基; R 3 和R 4 相同或不同,分别代表氢原子或烷基,或通过在其末端彼此结合形成亚烷基; A表示单键或亚甲基;和 X -表示阴离子)。 ;本发明的复合物具有优异的抗癌活性,并可用作药物,特别是抗癌剂。

著录项

  • 公开/公告号US2010121090A1

    专利类型

  • 公开/公告日2010-05-13

    原文格式PDF

  • 申请/专利权人 SUMIO KAIZAKI;

    申请/专利号US20080450470

  • 发明设计人 SUMIO KAIZAKI;

    申请日2008-03-27

  • 分类号C07F15;

  • 国家 US

  • 入库时间 2022-08-21 18:56:37

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