首页> 外国专利> Methods for preserving the viability of photoreceptor cells by anti-FAS-ligand/anti-FAS-receptor antibodies

Methods for preserving the viability of photoreceptor cells by anti-FAS-ligand/anti-FAS-receptor antibodies

机译:通过抗FAS配体/抗FAS受体抗体保持感光细胞活力的方法

摘要

Provided are methods and compositions for maintaining the viability of photoreceptor cells following retinal detachment. The viability of photoreceptor cells can be preserved by administering an apoptosis inhibitor to a mammal having an eye with retinal detachment. The apoptosis inhibitor maintains the viability of the photoreceptor cells until such time that the retina becomes reattached to the underlying retinal pigment epithelium and choroid. The treatment minimizes the loss of vision, which otherwise may occur as a result of retinal detachment.
机译:提供了用于在视网膜脱离后维持感光细胞的活力的方法和组合物。通过将凋亡抑制剂给予具有视网膜脱离的眼睛的哺乳动物,可以保持感光细胞的活力。凋亡抑制剂一直维持感光细胞的活力,直到视网膜重新附着在下面的视网膜色素上皮和脉络膜上为止。这种治疗可以最大程度地减少视力丧失,否则视力丧失可能由于视网膜脱离而发生。

著录项

  • 公开/公告号US7811832B2

    专利类型

  • 公开/公告日2010-10-12

    原文格式PDF

  • 申请/专利权人 DAVID ZACKS;JOAN W. MILLER;

    申请/专利号US20040892787

  • 发明设计人 DAVID ZACKS;JOAN W. MILLER;

    申请日2004-07-16

  • 分类号G01N33/53;A61K49/16;A61K38;A61K39/395;A61K39;C12N5;C12N5/079;C12N5/071;

  • 国家 US

  • 入库时间 2022-08-21 18:53:40

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