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Oxycontin controlled release formulations and methods of using same

机译:奥施康定控释制剂及其使用方法

摘要

The compositions disclosed herein are of use for the treatment of a wide variety of diseases. In particular, the compositions provide oxytocin and oxytocin analogs in sustained release formulations. In particular embodiments, the disclosed compositions concern oxytocin and oxytocin analogs, each of which may be associated with a biodegradable polymer and/or attached to a hydrophilic polymer. The methods include treatment of a wide variety of diseases and conditions. In particular, the methods include treatment of sexual dysfunction and disorders associated with repetitive behaviors, such as autism. The usefulness of the present invention is that the oxytocin, oxytocin analogs and mixtures thereof can be administered in a pharmaceutical formulation that increases their half-life and also provides for sustained release.
机译:本文公开的组合物可用于治疗多种疾病。特别地,该组合物以缓释制剂的形式提供催产素和催产素类似物。在特定的实施方案中,公开的组合物涉及催产素和催产素类似物,它们各自可以与生物可降解的聚合物缔合和/或连接至亲水性聚合物。该方法包括治疗多种疾病和状况。特别地,这些方法包括治疗性功能障碍和与重复行为有关的疾病,例如自闭症。本发明的有用之处在于,催产素,催产素类似物及其混合物可以以药物制剂的形式给药,从而增加了它们的半衰期并且还提供了持续释放。

著录项

  • 公开/公告号US2010143485A1

    专利类型

  • 公开/公告日2010-06-10

    原文格式PDF

  • 申请/专利权人 PAUL S. HUDNUT;GARY P. COOK;

    申请/专利号US20040547958

  • 发明设计人 PAUL S. HUDNUT;GARY P. COOK;

    申请日2004-03-05

  • 分类号A61K9/50;A61K38/22;A61P15;A61P25;

  • 国家 US

  • 入库时间 2022-08-21 18:52:42

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