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Bactericide against Streptococcus mutans and Streptococcus sobrinus

机译：变形链球菌和sobrinus链球菌的杀菌剂

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摘要

The present invention provides an enzyme with lytic activity against cariogenic bacteria and a means for treating and preventing tooth decay using the enzyme. The enzyme provided by the present invention is a lytic enzyme produced by Streptococcus mutans and has a substrate specificity for lysing selectively Streptococcus mutans and Streptococcus sobrinus. Therefore, application of the enzyme enables to remove selectively cariogenic bacteria or to decrease the number of cariogenic bacteria inside oral cavity, and may exert preventive effect against tooth caries. 展开▼

机译：本发明提供了一种对龋齿细菌具有裂解活性的酶，以及使用该酶治疗和预防蛀牙的方法。本发明提供的酶是由变形链球菌产生的裂解酶，并且具有选择性裂解变形链球菌和纤溶链球菌的底物特异性。因此，酶的应用能够选择性地去除龋齿细菌或减少口腔内的龋齿细菌的数量，并且可以发挥对龋齿的预防作用。 展开▼

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公开/公告号US7776325B2

专利类型

公开/公告日2010-08-17

原文格式PDF

申请/专利权人 MOTOYUKI SUGAI;HITOSHI KOMATSUZAWA;
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申请/专利号US20040583127

发明设计人 MOTOYUKI SUGAI;HITOSHI KOMATSUZAWA;
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申请日2004-11-29

分类号A61K38/43;

国家 US

入库时间 2022-08-21 18:51:35

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3. BACTERICIDE AGAINST STREPTOCOCCUS MUTANS AND STREPTOCOCCUS SOBRINUS [P] . CA2550013C . 2013-02-19

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