首页>
外国专利>
Activity-based probes for protein tyrosine phosphatases
Activity-based probes for protein tyrosine phosphatases
展开▼
机译:基于活性的蛋白质酪氨酸磷酸酶探针
展开▼
页面导航
摘要
著录项
相似文献
摘要
Provided are compounds capable of covalently binding to a protein tyrosine phosphatase (PTP). The compounds comprise Formula A:; ;Also provided are compositions comprising one of the above compounds covalently bound to a member of the PTP superfamily, methods of labeling a PTP using the compounds, methods of isolating a PTP from a mixture of proteins using the compounds, methods of evaluating whether a substance is an inhibitor of a PTP using the compounds, methods of evaluating the specificity of an inhibitor of a PTP using the compounds, methods of identifying a PTP involved in a disease in a mammal using the compounds, and methods of diagnosing a disease in a mammal using the compounds.
展开▼