首页>
外国专利>
PATHOLOGICALLY RELEVANT TUMOR MICROENVIRONMENTS FOR HIGH-THROUGHPUT DRUG SCREENING
PATHOLOGICALLY RELEVANT TUMOR MICROENVIRONMENTS FOR HIGH-THROUGHPUT DRUG SCREENING
展开▼
机译:与病理相关的肿瘤微环境,用于高剂量药物筛查
展开▼
页面导航
摘要
著录项
相似文献
摘要
A three-dimensional cell culture system is provided comprising one or more cell types of interest incorporated in a natural or synthetic hydrogel. An apparatus for high-throughput drug screening is also provided comprising a plurality of three-dimensional cell culture systems and a dispenser for placing at least one three-dimensional cell culture system into a pre-determined well of a multiwell plate. A method for high-throughput drug screening is also provided that comprises providing a test agent, providing a three-dimensional cell culture system, determining a first cellular response of the cell of interest before culturing in the presence of the agent, culturing the cell of interest in the cell culture system in the presence of the agent, determining a second cellular response of the cell of interest after culturing in the presence of the agent, and comparing the first and second cellular responses.
展开▼