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Polypeptide factor from a thermophilic eubacterial species and use thereof in the production of functional, heterologous proteins in an expression host

机译：来自嗜热真细菌物种的多肽因子及其在表达宿主中产生功能性异源蛋白质的用途

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摘要

A polypeptide factor derived from the thermophilic eubacterial species Thermus thermophilus has universal protein expression-assisting activity. The polypeptide factor has been named the CzrB protein active in full length or truncated form has the potential to act as a universal protein expression-assisting molecule which can increase the yields of all heterologous proteins produced in E. coli by a mechanism that is independent of the protein being expressed.

机译：嗜热嗜热菌种 Thermus thermophilus 衍生的多肽因子具有普遍的蛋白质表达辅助活性。多肽因子被称为具有全长或截短形式活性的CzrB蛋白，具有作为通用蛋白表达辅助分子的潜力，该分子可以提高在 E中产生的所有异源蛋白的产量。的机制与表达的蛋白质无关。 展开▼

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公开/公告号US7723072B2

专利类型

公开/公告日2010-05-25

原文格式PDF

申请/专利权人 JOSEPH TONY PEMBROKE;STEFANIA SPADA;JOHN GERARD WALL;
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申请/专利号US20070944511

发明设计人 JOHN GERARD WALL;STEFANIA SPADA;JOSEPH TONY PEMBROKE;
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申请日2007-11-23

分类号C12P21/06;C07H17/00;C07K14/00;

国家 US

入库时间 2022-08-21 18:50:23

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机译：嗜热菌种的多肽因子及其在表达宿主功能性杂种蛋白生产中的用途

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机译：来自嗜热真细菌物种的多肽因子及其在表达宿主中产生功能性异源蛋白质的用途

5. Polypeptide factor from a thermophilic eubacterial species and use thereof in the production of functional, heterologous proteins in an expression host [P] . 美国专利： US2004253592A1 . 2004-12-16

机译：来自嗜热真细菌物种的多肽因子及其在表达宿主中产生功能性异源蛋白质的用途

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