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Approaches to identify less harmful tobacco and tobacco products
Approaches to identify less harmful tobacco and tobacco products
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机译:识别危害较小的烟草和烟草制品的方法
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摘要
Aspects of the invention concern methods for detecting, identifying and evaluating tobacco and tobacco products to determine the potential that these compositions have to contribute to a tobacco-related disease. It is based, at least in part; on the discovery that exposure of pulmonary cells to smoke or smoke condensate obtained from tobacco or tobacco products induces double stranded breaks in cellular DNA, which were efficiently detected using assays that measure the presence, absence, or amount of phosphorylation of the histone, H2AX.
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