首页> 外国专利> Biospecific bivalent antibodies include light and heavy chains of an antibody that binds to the first antigen dominated by CH1 instead of CH3, and a light and heavy chain of an antibody that binds to the second antigen, in which CH3 is dominated by chlorine instead of Met. Prepare, and compose.

Biospecific bivalent antibodies include light and heavy chains of an antibody that binds to the first antigen dominated by CH1 instead of CH3, and a light and heavy chain of an antibody that binds to the second antigen, in which CH3 is dominated by chlorine instead of Met. Prepare, and compose.

机译:生物特异性二价抗体包括与CH1而不是CH3为主的第一抗原结合的抗体的轻链和重链,以及CH3而不是Met为主的CH2与抗体结合的轻链和重链。 。准备并撰写。

摘要

Biological specific bivalent antibody includes a light and heavy chain of antibody, which is connected with the first antigen with ch1 instead of CH3, and a light and heavy chain with CH3 instead of chlorine; preparation method and composition.
机译:生物特异性二价抗体包括轻链和重链,该轻链和重链与第一个抗原用ch1代替CH3,以及轻链和重链与CH3代替氯。制备方法和组成。

著录项

  • 公开/公告号CL2008003782A1

    专利类型

  • 公开/公告日2010-02-12

    原文格式PDF

  • 申请/专利权人 F. HOFFMANN-LA ROCHE AG.;

    申请/专利号CL20080003782

  • 发明设计人 KLEIN CHRISTIAN;SCHAEFER WOLFGANG;

    申请日2008-12-17

  • 分类号A61K39/395;C07K16/46;C07K19/00;C12N15/13;

  • 国家 CL

  • 入库时间 2022-08-21 18:47:15

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