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COMPOUNDS WITH THE COMBINATION OF ANTAGONISTIC ACTIVITY WITH RESPECT TO CANANABINOID RECEPTORS OF SVI INHIBITIVE ACTIVITY WITH RESPECT TO ACETYL CHOLINESTERASE
COMPOUNDS WITH THE COMBINATION OF ANTAGONISTIC ACTIVITY WITH RESPECT TO CANANABINOID RECEPTORS OF SVI INHIBITIVE ACTIVITY WITH RESPECT TO ACETYL CHOLINESTERASE
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机译:与抗活性和抗乙酰胆碱酯酶的SVI抑制活性有关的化合物
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摘要
This invention relates to compounds having a combination of antagonistic activity against the cannabinoid CB receptor and inhibitory activity against cholinesterase, to pharmaceutical compositions containing these compounds, to methods for producing compounds, to methods for producing new intermediates used for their synthesis, and to methods for producing compositions . The invention also relates to the use of such compounds and compositions, in particular for the treatment of Alzheimer's disease, cognitive impairment, memory impairment, dementia, attention deficits, traumatic brain damage, drug dependence, dependence and substance abuse. In particular, this invention relates to compounds of the general formula (1), wherein the symbols have the meanings indicated in the description.
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