RECOMBINANT MODIFIED VACCINIA ANKARA VIRUS COMPRISING A HETEROLOGOUS DNA SEQUENCE INSERTED INTO AN INTERGENIC REGION OF THE VIRAL GENOME AND VACCINE COMPRISING SAID VIRUS

摘要

The present invention relates to novel insertion sites useful for the integration of exogenous sequences into the Modified Vaccinia Ankara (MVA) virus genome. The present invention further provides plasmid vectors to insert exogenous DNA into the genome of MVA. Furthermore, the present invention provides recombinant MVA comprising an exogenous DNA sequence inserted into said new insertion site as medicine or vaccine.