USE OF LONG-CHAIN ALCOHOL DERIVATIVES FOR THE TREATMENT OF ALOPECIA AREATA

摘要

Disclosed is a method of treating alopecia areata using a compound having the formula:(I), wherein R1 is C10-C24 alkenyl; R2 is H, C1-C6 alkyl, aryl, or aralkyl, where any aryl moiety may be unsubstituted or substituted by nitro, cyano, halo, hydroxyl, NR6R7, or CR8R8NR6R7, where R6, R7, and R8 each independently is H or C1-C6 alkyl; and R3 and R4 each independently is H or C1-C6 alkyl, or R3 and R4 together with the nitrogen atom to which they are attached form a 5-7 membered heterocyclic saturated ring optionally containing an additional N or O, which is unsubstituted or substituted by C1-C6 alkyl, or an enantiomer or a pharmaceutically acceptable salt of the compound.