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METHOD FOR DETERMINING ENANTIOMERIC PURITY OF DARIFENACIN AND INTERMEDIATES
METHOD FOR DETERMINING ENANTIOMERIC PURITY OF DARIFENACIN AND INTERMEDIATES
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机译:菊酯和中间体的对映体纯度的测定方法
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摘要
The present invention relates to a method for differentiating and quantifying the enantiomers, thereby determining the enantiomeric purity, of darifenacin and its intermediate compounds and salts thereof. In addition, the invention relates to a method for differentiating and quantifying the enantiomers, thereby determining the enantiomeric purity of compounds of formula (I): wherein Y is hydrogen or a substituent of the formula (II): including the differentiation and quantification of compounds of formula (I) of varying enantiomeric purity from their corresponding enantiomers. The invention further relates to a process for preparing enantiomerically pure darifenacin using enantiomerically pure starting compounds which have been previously differentiated and quantified according to the method of the invention.
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