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AN ORAL MICROEMULSION FORMULATION WITH IMPROVED BIOAVAILABILITY AND STABILITY FOR TREATMENT OF ERECTILE DYSFUNCTION
AN ORAL MICROEMULSION FORMULATION WITH IMPROVED BIOAVAILABILITY AND STABILITY FOR TREATMENT OF ERECTILE DYSFUNCTION
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机译:具有改善的生物利用度和稳定性的口腔微乳剂,可治疗勃起功能障碍
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摘要
The present invention is about an oral microemulsion formulation of PDE5 inhibitor to achieve improved bioavailability with good stability. The microemulsion of the active agent was prepared by using surfactant, cosvriactant and oil phase in specific ratio to achieve the desired result of stability with improved bioavailability. Further the present invention provides a method of treating erectile dysfunction, which comprises administering to a patient need thereof an oral microemulsion containing PDE5 inhibitor. The invention further provides the use of oral microemulsion comprising a selective PDE5 inhibitor for treatment of erectile dysfunction.
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